Pyometra in unspayed female dogs (womb infection)
An unspayed female dog showing illness in the weeks after a season needs urgent vet review — pyometra is a life-threatening womb infection.
Recognise the signs
- Open pyometra — pus or bloody discharge from the vulva, often with a foul smell
- Closed pyometra — no discharge, but the dog becomes severely ill (more dangerous because of the missing warning sign)
- Drinking and urinating much more than usual
- Off food, vomiting, lethargy
- Distended belly (pus-filled womb)
- Pale gums, fast breathing, collapse in severe cases
- Often reaches the vet 2–8 weeks after the last season
First aid steps
- Phone the vet immediately and describe the signs.
- Note the date of the most recent season.
- Do not give food or water if the dog is vomiting.
- Carry the dog to the car if weak or collapsed.
- Drive to the practice without delay.
Do NOT
- Do not assume an unspayed female who is 'just a bit off' a few weeks after a season can wait — closed pyometra can kill within 24–48 hours.
- Do not give human painkillers.
- Do not delay for a 'wait and see' approach.
- Do not assume vaginal discharge is just leftover from the season — discharge weeks later is abnormal.
While transporting to the vet
- Keep the dog warm and as comfortable as possible.
- Phone ahead — IV fluids, bloods, ultrasound, and surgery may be prepared.
- Bring a record of recent seasons, weight, and any current medications.
When to phone the vet immediately
- Any unspayed female dog with vaginal discharge, increased thirst, off food, or vomiting in the weeks after a season
- Pale gums, weakness, collapse
- Distended belly
- Suspected closed pyometra (very ill dog with no discharge)
Common causes
- Unspayed female dogs, typically 4–8 weeks after a season
- Hormonal changes during the dioestrus phase create conditions for bacterial infection
- Risk increases with age — most cases over 6 years
- Mismating injections and some progesterone treatments raise risk
What the vet will need to know
- Spay status (always confirm)
- Date of most recent season
- Any vaginal discharge — colour, smell, amount
- Drinking and urinating volume changes
- Appetite and energy
- Any recent hormone treatments or mismating injection
Aftercare
- Surgical removal of the uterus and ovaries (ovariohysterectomy) is the standard of care — essentially an emergency spay on a sick dog.
- Hospitalisation typically 2–5 days with IV fluids and antibiotics.
- Recovery at home: rest, buster collar, short lead walks for 10–14 days.
- Most dogs recover well; outcomes are far better with prompt surgery.
Prevention
- Spaying is the only fully effective prevention — almost eliminates pyometra risk.
- Discuss timing of spay with the vet for individual dogs (not all breeds benefit from the same timing).
- Avoid hormone treatments where possible.
- If keeping a bitch entire for breeding, owners need to know the warning signs and have a clear plan for retirement and spay.
Breed-specific notes
- Higher pyometra incidence: Bernese Mountain Dog, Rottweiler, Rough Collie, Cavalier King Charles Spaniel, Golden Retriever, Leonberger, English Bulldog.
- Risk rises with age in all breeds.
Frequently asked questions
Why is closed pyometra more dangerous than open?
In a closed pyometra, the cervix stays shut and pus accumulates in the uterus with no external warning sign. The dog becomes severely ill from septicaemia and uterine rupture is a real risk. Open pyometra with discharge looks more dramatic but often presents earlier, when the dog is less unwell.
Can pyometra be treated without surgery?
In a select group of stable, breeding-quality bitches, medical management with prostaglandins and antibiotics is sometimes attempted — but it is risky, often unsuccessful, and not appropriate for sick or non-breeding dogs. Surgery remains the standard treatment.
When during the cycle does pyometra develop?
Usually 2–8 weeks after a season, in the dioestrus phase when progesterone levels are high. Owners often notice the first signs around 4–6 weeks post-season. This is the window to be most alert in unspayed females.